"Nail-Bed
Squamous Cell Carcinoma (SCC)
Digital SCC is a malignant tumor that
originates in the nail-bed epithelium.
Most dogs with SCC of the digit are
examined because of a sore toe. Limping, swelling,
bleeding/discharge, ulceration, and breaking or splitting of
nails are also common complaints. SCC tumors in many dogs were
preceded by chronic nail-bed infections.
Black, large breed dogs such as
Labrador Retrievers, Giant Schnauzers and Standard Poodles
appear to be predisposed. In these breeds, multiple digits may
be involved over a course of two to four years. Each toe
affected is a primary tumor, and not metastases from another
digit.
Squamous Cell Carcinoma of the digit is
locally aggressive, and "lysis" (erosion and
deterioration of bone) is evident on X-rays about 80% of the
time. Amputation of the digit is necessary to prevent SCC from
spreading to adjacent lymph nodes and major organs.
Average age at the onset of SCC is
nine, but Standard Poodles as young as four have been reported.
Diagnosis is confirmed by
histopathology of the affected digit."
Thanks Lynn! If someone
reading this information can help in this research, please
contact Lynn Wilkes at: Lynn@poodletoecancer.com